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Recovery Profile After General Anaesthesia in Paediatric Ambulatory Surgeries: Desflurane Versus Propofol
Aditi Jain1, Satinder Gombar1, Vanita Ahuja1
1Department of Anaesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India.
Turkish Journal of Anaesthesiology and Reanimation
|August 25, 2018
Summary
Propofol and desflurane offer similar recovery profiles for pediatric ambulatory surgery. Propofol is a more cost-effective anesthetic choice for these procedures.
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Pharmacology
Background:
- Ambulatory surgery in children requires rapid, safe recovery.
- Short-acting anesthetics like propofol and desflurane are crucial for this.
- Entropy monitoring aids in precise anesthetic delivery.
Purpose of the Study:
- To compare recovery profiles of pediatric patients undergoing ambulatory surgery.
- To evaluate general anesthesia (GA) using desflurane versus propofol.
- To assess anesthetic efficacy and safety in pediatric ambulatory settings.
Main Methods:
- Prospective randomized study of 80 children (3-10 years), ASA I/II.
- Entropy monitoring (State and Response Entropy 40-60) for anesthetic depth.
- Analysis of awakening time, hemodynamics, recovery, adverse events, and cost.
Main Results:
- No significant differences in blood pressure, CO2, or oxygen saturation.
- Desflurane group showed higher mean heart rate.
- Trends towards faster recovery in the desflurane group were not statistically significant.
- No serious adverse events; desflurane was more expensive than propofol.
Conclusions:
- Both desflurane and propofol provide comparable recovery profiles for pediatric ambulatory surgery.
- Propofol is a more cost-effective anesthetic option.
- Entropy-guided GA is safe and effective in this population.
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