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Updated: Feb 6, 2026

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
Published on: July 29, 2021
Effects of silk solution against laminectomy-induced dural adhesion formation and inflammation in a rat model
Yong-Jun Cho1, Chi Hern Lee2, Dae Won Kim3
11Department of Neurosurgery, Hallym University Medical Center, Chuncheon.
Abstract:
The authors investigated the effects of a silk solution against laminectomy-induced dural adhesion formation and inflammation in a rat model. They found that it significantly reduced postlaminectomy dural adhesion formation and inflammation. Dural adhesion formation, thought to be an inevitable consequence of laminectomy, is one of the most common complications following spinal surgery, and the authors' results indicate that the silk solution might be a potential novel therapeutic agent for dural adhesion formation.
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