Long-Term Functioning and Participation Across the Life Course for Preterm Neonatal Intensive Care Unit Graduates

Frances A Carter1, Michael E Msall2

  • 1Department of Psychology, The Center for Early Childhood Research, University of Chicago, 5848 S. University Avenue, Chicago, IL 60637, USA.

Clinics in Perinatology
|August 27, 2018
PubMed

Insights

Long-term outcomes for preterm infants require comprehensive life-course assessments beyond survival. Evaluating functional development and providing early support optimizes lifelong health and community participation for these vulnerable children.

Area of Science:

  • Neonatal neuroscience
  • Developmental pediatrics
  • Longitudinal health outcomes

Background:

  • Preterm birth poses significant risks to brain development.
  • Neonatal morbidities like bronchopulmonary dysplasia and sepsis impact long-term function.
  • Current assessments often focus narrowly on survival and early development.

Purpose of the Study:

  • To examine life-course trajectories of risk and resilience in the preterm neonatal brain.
  • To advocate for comprehensive functional outcome evaluations beyond standard neonatal assessments.
  • To identify key areas for proactive support to optimize lifelong well-being.

Main Methods:

  • Population-based analysis of functional outcomes across childhood, adolescence, and adulthood.
  • Moving beyond traditional neonatal morbidity counts (e.g., BPD, ROP, sepsis).
  • Utilizing comprehensive assessments beyond the Bayley Scales of Infant Development.

Main Results:

  • Survival alone is insufficient for understanding preterm infant neurodevelopmental outcomes.
  • A broader, life-course perspective is crucial for assessing functional trajectories.
  • Early and ongoing family and child support significantly impacts long-term functioning.

Conclusions:

  • Clinicians must adopt a life-course approach to evaluate preterm infant outcomes.
  • Comprehensive assessments are needed to capture the full spectrum of functional development.
  • Proactive family and developmental support is essential for optimizing academic, social, and vocational success.

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