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Related Concept Videos

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

952
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
952
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

3.8K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
3.8K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

903
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
903
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

348
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
348
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

983
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
983
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

330
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
330

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Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
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[How to diagnose heart-failure?]

Yu-Ching Liu1, Otmar Pfister1

  • 11 Klinik für Kardiologie, Universitätsspital Basel.

Therapeutische Umschau. Revue Therapeutique
|August 28, 2018
PubMed
Summary
This summary is machine-generated.

Diagnosing heart failure involves recognizing clinical signs and symptoms. Natriuretic peptides (BNP and NT-proBNP) help confirm the diagnosis, which is finalized with echocardiography to assess cardiac structure and function.

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Area of Science:

  • Cardiology
  • Public Health

Background:

  • Heart failure is an increasing public health concern due to demographic shifts, particularly the growing elderly population.
  • Clinical presentation of heart failure is characterized by signs and symptoms of increased cardiac filling pressure, congestion, and hypoperfusion.

Purpose of the Study:

  • To outline the diagnostic approach for heart failure.
  • To highlight the role of natriuretic peptides and echocardiography in confirming the diagnosis.

Main Methods:

  • Clinical assessment of signs and symptoms suggestive of heart failure.
  • Measurement of natriuretic peptides (BNP and NT-proBNP) to support or exclude the diagnosis.
  • Echocardiography to identify underlying structural or functional cardiac abnormalities.

Main Results:

  • Clinical signs and symptoms raise suspicion for heart failure.
  • Elevated natriuretic peptide levels corroborate the working diagnosis.
  • Echocardiography confirms heart failure diagnosis by revealing cardiac alterations.

Conclusions:

  • A multi-step diagnostic process is essential for accurate heart failure diagnosis.
  • Natriuretic peptides and echocardiography are crucial tools in the diagnostic pathway.
  • Early and accurate diagnosis is vital for managing this growing public health issue.