Related Experiment Video
Updated: Feb 6, 2026

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
Published on: May 21, 2010
[Clinical features of 63 patients with ataxia]
Paula Saffie Awad1, Felipe Vial Undurraga2, Pedro Chaná-Cuevas3
1Universidad de los Andes, Santiago, Chile.
Background:
Ataxia can be classified as genetic, sporadic or acquired.
Aim:
To report the clinical features of a group of patients with ataxia.
Material And Methods:
Review of medical records of patients consulting in a specialized center in movement disorders. Those records in which the diagnosis of "ataxia" or "ataxic syndrome" appeared, were selected for the review.
Results:
Of 4,282 records surveyed, the diagnosis of ataxia appeared in 95. After eliminating repeated or incomplete records, 63 were reviewed.
Results:
Ataxia was sporadic, genetic and acquired in 27, 22 and 14 patients, respectively. The mean age at presentation for genetic, acquired and sporadic ataxia was 24, 46 and 53 years respectively. All autosomal dominant ataxias were type 3 spinocerebellar ataxia (SCA). Friedrich's ataxia was the most common recessive form. Most sporadic forms of ataxia were multiple system atrophy with predominant cerebellar ataxia (MSA-C) subtype.
Conclusions:
Considering the heterogeneity of patients with ataxia, we propose a method to approach them.
More Related Videos
Related Concept Videos
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Endocarditis II: Clinical Features of Infective Endocarditis
Pericarditis II: Clinical Features and Diagnostic Tests
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Myocarditis II: Clinical Features and Diagnostic Tests

