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Related Experiment Video

Updated: Feb 5, 2026

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

Directional control of a processive molecular hopper.

Yujia Qing¹, Sandra A Ionescu¹, Gökçe Su Pulcu¹

¹Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK.

Science (New York, N.Y.)

|September 1, 2018

Summary

Scientists controlled a single molecular hopper

Area of Science:

Nanotechnology and Molecular Machines
Biophysics
Materials Science

Background:

Controlling molecular motion is crucial for developing nanoscale machines.
Previous efforts have faced challenges in achieving precise and directional movement.
The development of molecular motors with desired characteristics remains an active research area.

Purpose of the Study:

To demonstrate precise control over a single molecular hopper's motion.
To investigate the feasibility of using molecular hoppers for cargo transport.
To assess the potential of this system for applications like nanopore sequencing.

Main Methods:

Monitoring individual 0.7-nanometer steps of a molecular hopper.
Utilizing an electric field and a chemical ratchet within a nanopore.

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Functionalizing the hopper to carry molecular cargos, such as DNA.

Main Results:

The molecular hopper exhibited controlled, directional movement with defined start and end points.
The hopper demonstrated processivity without requiring chemical fuel.
Successful transport of a DNA molecule along the track was achieved.

Conclusions:

A controllable molecular hopper with desirable motion characteristics has been developed.
This system shows promise for precise cargo manipulation at the nanoscale.
The technology is a potential prerequisite for advancements in nanopore sequencing and other molecular technologies.