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Myeloperoxidase Inhibition Improves Ventricular Function and Remodeling After Experimental Myocardial Infarction

Muhammad Ali1, Benjamin Pulli1,2, Gabriel Courties1

  • 1Center for Systems Biology, and the Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

JACC. Basic to Translational Science
|September 1, 2018
PubMed

Keywords:
CNR, contrast to noise ratioEDV, end-diastolic volumeEF, ejection fractionIRI, ischemia reperfusion injuryLAR, lesion activation ratioLy-6C, lymphocyte antigen 6CMI, myocardial infarctionMPO, myeloperoxidaseMPO-Gd, bis-5-hydroxytryptamide-diethylenetriaminepentaacetate-gadoliniumMPO−/−, myeloperoxidase knock outinflammationmyeloperoxidasemyocardial infarctionoxidative stresstreatment

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