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Bilateral endoscopic optic nerve decompression in an infant with osteopetrosis
Anagha Medsinge1, Christin Sylvester1, Elizabeth Tyler-Kabara2
1Department of Ophthalmology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.
Osteopetrosis can cause vision loss in children due to optic canal narrowing. Endoscopic surgery improved vision in a 6-month-old infant with osteopetrosis and compressive optic neuropathy.
Area of Science:
- Ophthalmology
- Neurology
- Pediatrics
Background:
- Osteopetrosis is a rare genetic bone disorder characterized by impaired osteoclast function and defective bone resorption.
- This leads to increased bone density and abnormal skeletal remodeling, often affecting cranial nerves.
- Optic canal narrowing in osteopetrosis is a significant cause of vision loss in pediatric patients due to optic nerve compression.
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