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Massive Osteolysis in Distal Shaft of Humerus: A Case Report on Vanishing Bone Disease

Sana Noman1, Seema Faiz1, Sohail Ahmed Khan1

  • 1Department of Radiology, Dow Institute of Radiology, Dow University of Health Sciences, Karachi.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|September 4, 2018
PubMed

Gorham-Stout disease is a rare disease characterised by endothelial proliferation of lymphatics and vessels. It is also known as vanishing bone disease. Increased vascularity and proliferation lead to progressive bony osteolysis. We report a case of a 17-year female diagnosed as having post traumatic Gorham-Stout disease. Being reported for the first time from our population, this will be an informative addition to the already available literature. On X-rays, initially there is osteopenia with patchy distribution followed by coalescence of osteopenic patches, erosion of cortex with soft tissue involvement, and finally bone resorption. MRI shows increased T2 signal with heterogeneous enhancement.

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