A Modified Resin Sealer: Physical and Antibacterial Properties
Juheon Seung1, Michael D Weir2, Mary Anne S Melo3
1Endodontics Division, Department of Advanced Oral Sciences and Therapeutics, School of Dentistry, University of Maryland Baltimore, Maryland.
Journal of Endodontics
|September 4, 2018
Summary
This study enhanced AH Plus resin sealer with nanosilver (NAg) and dimethylaminododecyl methacrylate (DMAHDM), improving its antibacterial properties against Enterococcus faecalis without compromising physical integrity.
Area of Science:
- Dental Materials Science
- Antimicrobial Agents
- Endodontics
Background:
- Resin sealers are crucial in root canal therapy.
- Incorporating antimicrobial agents can enhance sealer efficacy.
- Dimethylaminododecyl methacrylate (DMAHDM) and nanosilver (NAg) show promise as antimicrobial additives.
Purpose of the Study:
- To investigate the physical and antibacterial properties of AH Plus resin sealer modified with DMAHDM and NAg.
- To determine optimal concentrations of DMAHDM and NAg that do not compromise sealer physical properties.
- To evaluate the modified sealer's effectiveness against Enterococcus faecalis.
Main Methods:
- A pilot study determined non-altering concentrations of DMAHDM (2.5%) and NAg (0.15%) for AH Plus.
- Modified AH Plus (mAH Plus) was created.
- Antibacterial properties were assessed using a direct contact test against E. faecalis at 1, 7, and 14 days.
Main Results:
- Modified AH Plus exhibited significantly enhanced antibacterial activity against E. faecalis compared to unmodified AH Plus.
- The antibacterial effect persisted from day 1 through day 14.
- Physical properties (setting time, solubility, dimensional change) remained within acceptable standards, though flow was reduced.
Conclusions:
- The addition of 0.15% NAg and 2.5% DMAHDM to AH Plus is feasible.
- The modified AH Plus (mAH Plus) demonstrates significant and sustained antibacterial efficacy.
- This enhanced resin sealer holds potential for improved root canal disinfection.
Keywords:
Dental cementsEnterococcus faecalismodified direct contact testnanoparticlesquaternary ammoniumMore Related Videos
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