Related Experiment Video
Updated: Feb 5, 2026

07:01
Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules
Published on: September 16, 2022
2.2K
[Skin reactivity in allergic conjunctivitis].
Pablo Andrés Miranda-Machado1, Bautista De la Cruz-Hoyos Sánchez
1Universidad Nacional de Colombia, Bogotá, Colombia. mmpa9@hotmail.com.
Summary
In allergic conjunctivitis patients, 70.65% showed positive skin reactivity to allergens, with house dust mites being most common. Associated allergic conditions were frequent, indicating higher reactivity in complex cases.
Area of Science:
- Ophthalmology
- Allergology
- Immunology
Background:
- Allergic conjunctivitis involves IgE-mediated hypersensitivity to allergens.
- Sensitization to perennial and multiple allergens is common in these patients.
- Mast cell activation and inflammatory mediator release are key mechanisms.
Purpose of the Study:
- To determine the prevalence of positive skin reactivity to specific allergens.
- To identify common allergens in patients diagnosed with allergic conjunctivitis.
- Study conducted at an allergology clinic in Cartagena, Colombia.
Main Methods:
- Cross-sectional study design.
- Inclusion of 92 patients aged 3-74 years.
- Convenience sampling method utilized.
Main Results:
- 70.65% of patients exhibited positive skin prick tests to at least one allergen.
- House dust mites were the most prevalent allergen (65.2%).
- Associated allergic conditions included allergic rhinitis (51%), allergic asthma (23%), and atopic dermatitis (10%).
Conclusions:
- Positive skin reactivity to allergens is significant in allergic conjunctivitis patients.
- Patients with co-existing allergic conditions showed higher allergen reactivity.
- Highlights the importance of comprehensive allergy testing in managing allergic conjunctivitis.
Related Concept Videos
Allergic Reactions
32.4K
Overview
32.4K
Allergic Drug Reactions
1.5K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.5K
Cross-reactivity
33.1K
Overview
33.1K
Reactivity of Enols
4.1K
Enols are a class of compounds where a hydroxyl group is attached to a carbon–carbon double bond, which implies that it is a vinyl alcohol. A carbonyl compound with an α hydrogen undergoes keto–enol tautomerism and remains in equilibrium with its tautomer, the enol form. Usually, the keto tautomer is present in a higher concentration than the enol tautomer due to the higher bond energy of C=O compared to C=C. Moreover, the direction of the keto–enol equilibrium is...
4.1K
Reactivity of Enolate Ions
3.4K
Enolate ions are formed by the acid–base reaction of a carbonyl compound with a base. This leads to deprotonation of the α hydrogen atom, leading to a resonance-stabilized enolate ion where one of the contributing structures is an oxyanion, which imparts additional stability. Therefore, the proton on the α carbon is more acidic in nature than that of other sp3-hybridized C–H bonds but less acidic than those in O–H bonds where the negative charge in the conjugate...
3.4K
Radical Reactivity: Overview
2.8K
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired...
2.8K

