Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Specialized Characteristics of Cardiac Muscles01:27

Specialized Characteristics of Cardiac Muscles

4.2K
The primary role of cardiac muscles is to propel blood throughout the cardiovascular system. The cardiac muscle cells, or cardiomyocytes, exhibit specialized characteristics that allow them to perform this function.
Cardiac muscle cells are smaller than skeletal muscles, averaging 10–20 mm in diameter and 50–100 mm in length. However, they have large energy demands for continuous contraction and relaxation. This energy is almost exclusively derived from aerobic metabolism of energy...
4.2K
Physiology of the Heart: The Cardiac Cycle01:18

Physiology of the Heart: The Cardiac Cycle

9.5K
The cardiac cycle describes the events from one heartbeat to the next. It includes three main phases: diastole, atrial systole, and ventricular systole, all driven by changes in chamber pressures and the function of heart valves.
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
9.5K
Embryonic Stem Cells00:58

Embryonic Stem Cells

32.5K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.5K
Characteristics of Life01:23

Characteristics of Life

261.8K
Biology is a natural science that studies life and living organisms, including their structure, function, development, interactions, evolution, distribution, and taxonomy. The field's scope is extensive and divided into several specialized disciplines, such as anatomy, physiology, ethology, genetics, and many more. All living things share a few key traits, including cellular organization, heritable genetic material and the ability to adapt/evolve, metabolism to regulate energy needs, the...
261.8K
Adult Stem Cells01:33

Adult Stem Cells

33.9K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
33.9K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

28.1K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and safety of combination therapy with statin and ezetimibe in patients failing to achieve target LDL levels at cardiology outpatient clinics in Turkey (COM-TR-OLDL): a real-world observational study.

Lipids in health and disease·2026
Same author

Sex-Specific Heart Rate Variability Associations With Vitamin B12, Folate, and Iron Status.

Reviews in cardiovascular medicine·2026
Same author

Tinnitus, Dizziness and Hearing Status During Hypertension Diagnosis and Treatment.

The Annals of otology, rhinology, and laryngology·2026
Same author

Infectious agents, protein electrophoresis and immunoglobulin levels in patients with coronary artery ectasia.

Indian heart journal·2025
Same author

The Effect of Video Streaming With Virtual Reality Glasses During Arteriovenous Fistula Needle Insertion on Pain and Anxiety of Individuals Undergoing Hemodialysis Treatment.

Hemodialysis international. International Symposium on Home Hemodialysis·2025
Same author

Relationship between serum copeptin levels and non-invasive endothelial function indicators in dipper and non-dipper hypertensive patients.

American journal of cardiovascular disease·2025

Related Experiment Video

Updated: Feb 5, 2026

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
07:29

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

Published on: June 20, 2015

20.2K

Cardiac Stem Cell Characteristics in Physiological and Pathological Conditions.

Selçuk Öztürk1, Y Murat Elçin1,2

  • 1Ankara University Faculty of Science, Tissue Engineering, Biomaterials and Nanobiotechnology Laboratory, Ankara, Turkey.

Current Pharmaceutical Design
|September 5, 2018
PubMed
Summary

Cardiac stem cells (CSCs) offer heart regeneration potential. This review examines how physiological and pathological conditions affect CSC characteristics, crucial for effective cardiac regenerative medicine.

Keywords:
Cardiac stem cellscardiovascular diseasecell therapymyocardial infarctionpatient characteristicsregenerative medicine.

More Related Videos

Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells
08:00

Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells

Published on: January 12, 2015

8.6K
Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction
10:46

Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction

Published on: November 3, 2011

20.8K

Related Experiment Videos

Last Updated: Feb 5, 2026

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
07:29

Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies

Published on: June 20, 2015

20.2K
Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells
08:00

Derivation of Cardiac Progenitor Cells from Embryonic Stem Cells

Published on: January 12, 2015

8.6K
Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction
10:46

Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction

Published on: November 3, 2011

20.8K

Area of Science:

  • Cardiovascular Biology
  • Stem Cell Biology
  • Regenerative Medicine

Background:

  • The adult heart was historically considered post-mitotic.
  • Discovery of cardiac stem cells (CSCs) challenges this, offering potential for heart repair after myocardial infarction (MI).
  • CSCs can be sourced autologously or allogeneically for transplantation.

Purpose of the Study:

  • To review alterations in CSC characteristics under various physiological and pathological conditions.
  • To inform the selection of optimal CSC populations for cardiac regenerative therapies.
  • To enhance understanding of CSCs' regenerative capacity in different health states.

Main Methods:

  • Literature review of studies on CSC characteristics.
  • Analysis of CSC alterations in conditions including aging, MI, hypertension, diabetes, heart failure, and cancer.
  • Synthesis of findings regarding CSC biological activity and regenerative potential.

Main Results:

  • Various physiological (e.g., aging) and pathological conditions (e.g., hypertension, diabetes, cancer) significantly alter CSC characteristics.
  • These alterations impact the regenerative capacity and biological activity of CSCs.
  • Understanding these changes is vital for predicting CSC behavior in patients.

Conclusions:

  • CSC characteristics are dynamic and influenced by patient health status.
  • Knowledge of condition-specific CSC alterations is essential for successful cardiac regenerative medicine.
  • Further research is needed to define and utilize the most effective CSC populations for therapy.