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Updated: Feb 5, 2026

Quantification of Colonic Stem Cell Mutations
Published on: September 25, 2015
NGS-dataset of putative driver mutations associated with benign peritoneal strumosis
Michael Brockmann1, Verena Schildgen1, Oliver Schildgen1
1Kliniken der Stadt Köln gGmbH, Klinikum der Privaten Universität Witten/Herdecke, Institut für Pathologie, Ostmerheimer Str. 200, D-51109 Cologne, Germany.
Abstract:
A rare case of benign peritoneal strumosis was screened for driver mutations in genes relevant to currently approved cancer therapies. Therefore, three formalin fixed paraffin embedded issue sections were screened with the GeneReader Actionable Insights NGS panel (Qiagen, Hilden, Germany) for the occurrence of driver mutations. Several mutations were identified in drug-targetable genes, such as ALK, EGFR, and BRAF. The majority of identified mutations were single nucleotide variant, but also a insertion/deletion mutation was identified. The presented dataset is the first NGS dataset available from a patient with benign peritoneal strumosis.
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