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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

2.3K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Composition of Blood01:22

Composition of Blood

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The blood in our bodies comprises three major components: blood plasma, formed elements, and the extracellular matrix. Blood plasma is a yellowish fluid that constitutes 55% of the total blood volume. It is primarily made up of water and essential substances such as electrolytes and proteins. Blood plasma serves as a medium for transporting blood cells and also contains nutrients, enzymes, hormones, antibodies, and gases.
Formed elements constitute the remaining 45% of the blood volume. These...
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Blood Flow01:29

Blood Flow

76.0K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
76.0K
Blood Types02:20

Blood Types

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
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Blood Pressure01:24

Blood Pressure

10.2K
The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
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Updated: Feb 5, 2026

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
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Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

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Whole Blood Transfusion.

Andrew P Cap1, Andrew Beckett1, Avi Benov1

  • 1Joint Trauma System, 3698 Chambers Pass, Joint Base San Antonio, Fort Sam Houston, TX.

Military Medicine
|September 7, 2018
PubMed
Summary
This summary is machine-generated.

Whole blood is ideal for severe hemorrhage resuscitation, offering complete oxygen delivery and hemostasis. Low titer group O whole blood serves as a universal product for rapid, life-saving transfusions in trauma patients.

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Area of Science:

  • Transfusion Medicine
  • Trauma Resuscitation
  • Hematology

Background:

  • Severe traumatic hemorrhage necessitates rapid resuscitation.
  • Whole blood contains all essential oxygen-carrying and hemostatic components.
  • Low titer group O whole blood offers universal compatibility.

Purpose of the Study:

  • To evaluate the efficacy and safety of whole blood in resuscitation.
  • To highlight the role of low titer group O whole blood as a universal product.
  • To compare whole blood resuscitation with component therapy.

Main Methods:

  • Review of clinical data on whole blood transfusion in trauma.
  • Analysis of storage capabilities and hemostatic function of whole blood.
  • Assessment of low titer group O whole blood's universal applicability.

Main Results:

  • Whole blood provides essential elements for oxygen delivery and hemostasis.
  • Low titer group O whole blood can be transfused universally to unknown blood groups.
  • Stored whole blood retains hemostatic function for up to 35 days.
  • Clinical data suggest whole blood is equivalent or superior to component therapy.

Conclusions:

  • Low titer group O whole blood is the standard of care for major hemorrhage resuscitation.
  • Whole blood transfusion is a safe and effective resuscitation strategy.
  • Availability of stored or fresh whole blood ensures timely treatment for exsanguinating patients.