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Updated: Feb 5, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
Corneal tomographic features of postrefractive surgery ectasia
Pooja Khamar1, Ritika Dalal1, Rachana Chandapura2
1Department of Cornea and Refractive Surgery, Narayana Nethralaya Eye Hospital, Bangalore, India.
Abstract:
The purpose of this study was to evaluate the tomographic features of postrefractive surgery eyes. This was a retrospective evaluation of clinical data. Three patients with post-LASIK (laser-assisted in situ keratomileusis) and two patients with post-SMILE (small incision lenticule extraction) ectasia were imaged with Scheimpflug imaging (SI, Pentacam) and optical coherence tomography (OCT, RTVue). Curvature and wavefront aberrations of the air-epithelium interface (A-E) and epithelium-Bowman's layer interface (E-B) were derived. OCT of normal and keratoconic eyes from an earlier study were compared with the data of the ectasia eyes. Curvature and aberrometry of the A-E interfaces were statistically similar between SI and OCT. However, OCT revealed a steeper and more aberrated E-B interface than A-E though correlation between them was inferior to the correlation for keratoconic eyes. Furthermore, the magnitude of differences between the A-E and E-B interfaces was greater in the ectasia eyes than the keratoconic eyes. OCT could possibly assist better in selecting appropriate treatment plan for postrefractive surgery ectasia eyes than conventional tomographers.
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