Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is a Nervous System?01:25

What is a Nervous System?

105.1K
Overview
105.1K
Drug-Receptor Interactions01:29

Drug-Receptor Interactions

7.5K
Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. For instance, the binding of agonists activates the receptor to generate a cellular reaction, while antagonists bind to receptors without causing their activation.
Several parameters, such as the drug's affinity for its receptor and its efficacy, which is its ability to activate the receptor, determine the drug's effect on the tissue....
7.5K
Drug-Receptor Interaction: Antagonist01:28

Drug-Receptor Interaction: Antagonist

5.0K
An antagonist is a drug that binds strongly to a receptor without activating it. An antagonist prevents other molecules, such as neurotransmitters or hormones, from binding to the receptor and triggering a cellular response. Such interaction effectively hinders the normal physiological processes mediated by the receptor, resulting in various pharmacological effects depending on the specific receptor targeted.
Antagonists can be classified as competitive or noncompetitive based on their...
5.0K
Drug-Receptor Interaction: Agonist01:25

Drug-Receptor Interaction: Agonist

4.1K
Agonists are drugs that interact with specific receptors in the body to produce a biological response. When an agonist binds to a receptor, it activates or enhances the receptor's function, leading to physiological effects. The interaction between agonist drugs and receptors is crucial for their therapeutic action in various medical treatments.
Agonists can bind to receptors in different ways. Some agonists bind directly to the receptor's active site, mimicking the endogenous...
4.1K
The Parasympathetic Nervous System01:14

The Parasympathetic Nervous System

115.8K
Overview
115.8K
The Sympathetic Nervous System01:25

The Sympathetic Nervous System

103.9K
Overview
103.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Prevalence of periodontal disease among adolescents in the Nenets autonomous area].

Stomatologiia·2025
Same author

[Myocardial revascularization in chronic coronary artery disease. State of art].

Kardiologiia·2023
Same author

Direct and Indirect Neurological Signs of COVID-19.

Neuroscience and behavioral physiology·2021
Same author

Surface characterization and biological assessment of corrosion-resistant a-C:H:SiO<sub>x</sub> PACVD coating for Ti-6Al-4V alloy.

Materials science & engineering. C, Materials for biological applications·2021
Same author

[Direct and indirect neurological manifestations of COVID-19].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2020
Same author

[Surgical treatment of lung injuries and diseases in patients with blunt chest trauma].

Khirurgiia·2020

Related Experiment Video

Updated: Feb 5, 2026

Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration
07:08

Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration

Published on: July 31, 2013

20.2K

[INTERACTION OF GLUTAMATE AND GABA RECEPTORS IN THE CENTRAL NERVOUS SYSTEM].

V A Popov, V A Semenov, D V Amakhin

    Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
    |September 8, 2018
    PubMed
    Summary

    This study explores how GABA and glutamate receptors interact in central neurons. It details their co-localization, receptor structures, and functions, including ionotropic and metabotropic receptor interactions.

    More Related Videos

    Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster
    06:45

    Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster

    Published on: November 21, 2018

    12.4K
    Using an &#945;-Bungarotoxin Binding Site Tag to Study GABA A Receptor Membrane Localization and Trafficking
    11:57

    Using an α-Bungarotoxin Binding Site Tag to Study GABA A Receptor Membrane Localization and Trafficking

    Published on: March 28, 2014

    16.3K

    Related Experiment Videos

    Last Updated: Feb 5, 2026

    Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration
    07:08

    Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration

    Published on: July 31, 2013

    20.2K
    Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster
    06:45

    Electrophysiological Recording of The Central Nervous System Activity of Third-Instar Drosophila Melanogaster

    Published on: November 21, 2018

    12.4K
    Using an &#945;-Bungarotoxin Binding Site Tag to Study GABA A Receptor Membrane Localization and Trafficking
    11:57

    Using an α-Bungarotoxin Binding Site Tag to Study GABA A Receptor Membrane Localization and Trafficking

    Published on: March 28, 2014

    16.3K

    Area of Science:

    • Neuroscience
    • Molecular Biology

    Background:

    • GABA and glutamate are key neurotransmitters in the central nervous system.
    • Understanding their receptor interactions is crucial for neuronal function.

    Purpose of the Study:

    • To provide an overview of the postsynaptic interaction between GABA and glutamate receptors.
    • To discuss the co-localization, structure, and function of these receptors.

    Main Methods:

    • Literature review of existing research on GABA and glutamate receptors.
    • Analysis of studies detailing receptor co-localization and synaptic interactions.

    Main Results:

    • GABA and glutamate are frequently co-localized within the same synapses.
    • Both ionotropic and metabotropic glutamate and GABA receptors exhibit complex interactions.
    • The structure and function of these receptors are intricately linked to their postsynaptic activity.

    Conclusions:

    • Postsynaptic interactions between GABA and glutamate receptors are fundamental to central neuron signaling.
    • Further research into these interactions can reveal mechanisms underlying various neurological processes.