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Nontypable

Marianne Stærk1, Sara A Tolouee2, Jens J Christensen1,3

  • 1Department of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark.

The Open Microbiology Journal
|September 11, 2018
PubMed
Summary

Non-typable Haemophilus influenzae can cause urinary tract infections and septicemia, even in adults with kidney stones. Prompt antibiotic treatment is crucial, as this pathogen may be increasingly resistant.

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Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Urology

Background:

  • Haemophilus influenzae typically causes respiratory infections.
  • Non-typable strains are now a leading cause of invasive disease post-Hib vaccine.
  • Rarely reported as a cause of urinary tract infections (UTIs).

Observation:

  • A case of an adult male with non-typable Haemophilus influenzae septicemia and UTI.
  • Patient presented with flank pain, CT revealed bilateral renal and right ureteral stones causing obstruction.
  • Haemophilus influenzae identified in blood and urine cultures.

Findings:

  • The isolated strain, despite rising resistance trends, remained susceptible to all tested antibiotics.
  • Successful treatment involved intravenous cefuroxime, ureteric stenting, and oral ciprofloxacin.
Keywords:
Antibiotic resistanceHemophilus influenzae infectionInvasive diseaseNon-typableRenal stonesUrinary tract infection

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  • The patient recovered fully from the infection and obstruction.

    • Implications:

    • Highlights Haemophilus influenzae as a potential urinary pathogen, particularly with urinary tract abnormalities.
    • Emphasizes the need for awareness of antibiotic resistance patterns in Haemophilus influenzae.
    • Suggests considering Haemophilus influenzae in the differential diagnosis of UTIs, especially in at-risk patients.