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Model evaluation of rapid 4-dimensional lung tomosynthesis.
1Karmanos Cancer Institute, Wayne State University School of Medicine, Department of Oncology, Division of Radiation Oncology, Detroit, Michigan.
Advances in Radiation Oncology
|September 12, 2018
Summary
This study explores rapid lung digital tomosynthesis (DTS) using stationary x-ray sources to reduce artifacts in 4D CT scans. Promising results suggest feasibility with current imaging technology and developing cold cathode hardware.
Area of Science:
- Medical Imaging
- Radiological Physics
- Computational Imaging
Background:
- Current 4-dimensional computed tomography (CT) techniques for lung motion analysis suffer from anatomical uncertainties due to artifacts.
- Digital tomosynthesis (DTS) offers a potential alternative for reducing these artifacts.
- Rapid acquisition rates are crucial for accurately capturing thoracic motion.
Purpose of the Study:
- To investigate a novel lung motion digital tomosynthesis (DTS) model.
- To utilize stationary detectors and stationary cold cathode x-ray sources for high-speed projection acquisition.
- To reduce anatomical uncertainties and artifacts inherent in thoracic 4-dimensional CT.
Main Methods:
- Studied parameters for rapid 4D DTS using a conventional radiographic system and a hypothetical hardware model.
- Derived rapid imaging parameters (sweep duration, projections/sec, pulse duration, mA) based on motion capture, breathing rates, amplitude, and SNR.
- Collected and reconstructed anterior-posterior and lateral projection images of a thorax phantom with iodine inserts, simulating reduced x-ray output.
Main Results:
- DTS signal-to-noise ratio (SNR) of inserts was superior at clinical milliampere-seconds (mAs) compared to automatic exposure-control radiographs.
- Superior SNR was observed at 50% and 25% of standard DTS mAs in 3 out of 4 conditions.
- Identified demanding performance parameters for high-speed DTS, including projection rates up to 5862 projections/sec and specific mA values for AP and lateral imaging.
Conclusions:
- The feasibility of rapid lung DTS is contingent upon the performance of developing stationary cold cathode hardware.
- Current image receptor technology is capable of supporting the required frame acquisition rates for this DTS model.
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