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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

3.5K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.4K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.4K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.4K
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
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Related Experiment Video

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Acupuncture in a Rat Model of Asthma
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Dupixent, a New Entrant In the Asthma Lists.

Thomas Reinke

    Managed Care (Langhorne, Pa.)
    |September 15, 2018
    PubMed
    Summary

    Dupixent (dupilumab) may soon be approved for severe asthma, offering a new monoclonal antibody treatment. This biologic targets type 2 inflammation, joining existing options for severe allergic asthma patients.

    Area of Science:

    • Immunology
    • Pulmonology
    • Pharmacology

    Background:

    • Severe asthma is often characterized by type 2 inflammation.
    • Current biologic therapies target this inflammation, improving patient outcomes.
    • Dupixent (dupilumab) is an established treatment for atopic dermatitis.

    Purpose of the Study:

    • To evaluate the potential approval of Dupixent (dupilumab) for severe asthma.
    • To assess Dupixent's role as a monoclonal antibody for type 2 inflammation in asthma.

    Main Methods:

    • Review of FDA action dates and existing approvals for severe asthma biologics.
    • Analysis of Dupixent's mechanism of action in relation to type 2 inflammation.

    Main Results:

    Keywords:
    AsthmaMedication Managementdupilumab

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  • Dupixent (dupilumab) has an upcoming FDA action date for its asthma indication.
  • If approved, Dupixent will be a new monoclonal antibody option for severe asthma.
  • Conclusions:

    • Dupixent (dupilumab) is poised to become a new therapeutic option for severe asthma.
    • The drug's approval will expand treatment choices for patients with type 2 inflammation-driven severe asthma.