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Updated: Feb 5, 2026
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Automation of a Positron-emission Tomography PET Radiotracer Synthesis Protocol for Clinical Production
Published on: October 26, 2018
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PET/Computed Tomography and PET/MR Imaging: Basic Principles, Methodology, and Imaging Protocol for Musculoskeletal
Rahul V Parghane1, Sandip Basu1
1Radiation Medicine Centre (BARC), Tata Memorial Hospital Annexe, Parel, Mumbai 400012, India; Homi Bhabha National Institute, Mumbai 400094, India.
PET Clinics
|September 17, 2018
Summary
This review covers Positron Emission Tomography/Computed Tomography (PET/CT) and PET/Magnetic Resonance Imaging (PET/MRI) for musculoskeletal disorders. It details tracers, protocols, and compares the current roles and limitations of these imaging techniques.
Area of Science:
- Radiology
- Nuclear Medicine
- Musculoskeletal Imaging
Background:
- Musculoskeletal disorders require accurate diagnostic imaging.
- Positron Emission Tomography (PET) combined with Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) offers advanced visualization.
- Evaluating the utility of these hybrid imaging modalities is crucial.
Purpose of the Study:
- To review the fundamentals of PET/CT and PET/MRI for musculoskeletal disorders.
- To provide an overview of PET tracers and imaging protocols.
- To enumerate the current role and limitations of PET/CT and PET/MRI.
Main Methods:
- Review of existing literature on PET/CT and PET/MRI in musculoskeletal imaging.
- Discussion of Fluorodeoxyglucose (FDG) and non-FDG PET tracers.
- Analysis of various PET, CT, and MRI protocols.
Main Results:
- PET/CT and PET/MRI provide valuable insights into musculoskeletal conditions.
- Individualized application of different tracers and protocols is possible.
- Both modalities have specific strengths and weaknesses in clinical practice.
Conclusions:
- PET/CT and PET/MRI are essential tools in the evaluation of musculoskeletal disorders.
- Understanding their protocols and tracers allows for tailored patient management.
- Further research is needed to address the shortcomings of current techniques.
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