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Updated: Feb 4, 2026

Measuring Endoreduplication by Flow Cytometry of Isolated Tuber Protoplasts
Published on: March 9, 2018
The cutaneous manifestations of tuberous sclerosis complex
Quoc-Bao D Nguyen1, Mary D DarConte1, Adelaide A Hebert1
1Department of Dermatology, UTHealth McGovern Medical School, Houston, Texas.
Abstract:
Tuberous sclerosis complex (TSC) is a genetic multisystem disease with variable manifestations that can prominently involve the skin. The diagnosis of this disorder has evolved over the past two centuries. The 2012 TSC criteria emphasizes the importance of dermatological findings; orocutaneous manifestations account for 4 of 11 major criterion and 3 of 6 minor criterion. A detailed clinical dermatological evaluation is recommended for both pediatric and adult patients undergoing initial evaluation for TSC. Comprehensive dermatologic evaluation is extremely helpful when assessing these lesions and constructing a differential diagnosis.
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