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Organic Structure-directing Agent-free Synthesis for *BEA-type Zeolite Membrane

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Published on: February 22, 2020

Triflimide (HNTf₂) in Organic Synthesis.

Wanxiang Zhao¹, Jianwei Sun²

¹State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering , Hunan University , Changsha 410082 , P. R. China.

Chemical Reviews

|September 26, 2018

Summary

Triflimide (HNTf2) is a powerful super Brønsted acid catalyst. Its strong acidity and stable conjugate base make it superior to triflic acid in many organic synthesis applications.

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Area of Science:

Organic Chemistry
Catalysis

Background:

Triflimide (HNTf2) is a commercially available super Brønsted acid.
It exhibits strong acidity and compatibility with organic solvents.
Its conjugate base (Tf2N-) has low nucleophilicity and noncoordinating properties.

Purpose of the Study:

To review the synthesis, properties, and applications of triflimide in organic synthesis.
To highlight its advantages over traditional catalysts like triflic acid (TfOH).
To introduce the related reagent triflidic acid (HCTf3).

Main Methods:

Literature review of triflimide's use in organic reactions.
Analysis of triflimide's catalytic performance and properties.
Comparison with triflic acid and other related reagents.

Main Results:

Triflimide serves as an exceptional catalyst, promoter, and additive in diverse organic reactions.
It often outperforms triflic acid due to its unique properties.
It acts as a precursor for reactive cationic metal complexes and organic intermediates.

Conclusions:

Triflimide is a versatile and highly effective reagent in modern organic synthesis.
Its unique properties enable enhanced reactivity and catalytic activity.
Further exploration of triflimide and related compounds like triflidic acid is warranted.