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Updated: Feb 4, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
An Occupational Legacy: Malignant Mesothelioma Incidence and Mortality in Wisconsin
Carrie D Tomasallo1, Krista Y Christensen, Michelle Raymond
1Wisconsin Department of Health Services, Division of Public Health, Bureau of Environmental and Occupational Health, Madison, WI (Dr Tomasallo, Dr Christensen, Ms Raymond, Dr Creswell, Dr Anderson, and Dr Meiman); Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI (Dr Christensen); Department of Population Health Sciences, University of Wisconsin-Madison, Madison, WI (Ms Raymond, Dr Creswell, and Dr Anderson).
Objectives:
The aim of the study was to describe mesothelioma occurrence in Wisconsin from 1997 to 2013 by usual industry and occupation (I&O), including occupations generally considered low risk.
Methods:
Population-based rates and standardized incidence and mortality ratios were calculated. Two case-control analyses were designed to compare mesothelioma incidence and mortality in specific I&O groups with occurrence of (1) brain and central nervous system cancers and (2) other causes of death, using logistic regression.
Results:
Mesothelioma incidence and mortality were elevated in Wisconsin (SIRadj = 1.20 [1.13 to 1.28]; SMRadj = 1.30 [1.22 to 1.38]). Certain industry (construction, manufacturing) and occupation (construction and extraction) groups were associated with increased odds of mesothelioma, with some evidence of increased risk among teachers.
Conclusions:
Forty years after the Occupational and Safety Health Act, mesothelioma incidence and mortality remain elevated in Wisconsin, with increased risk continuing for certain I&O groups.
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