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Updated: Feb 4, 2026

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Aortic Ring Assay
Published on: November 24, 2009
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Screening for thoracic aortic pathology: Clinical practice in a single tertiary center
Lidia R Bons1, Lucas Uchoa de Assis1, Silvy Dekker1
1Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Congenital Heart Disease
|September 28, 2018
Summary
Computed tomography (CT) is recommended for thoracic aortic screening due to transthoracic echocardiography (TTE) having low sensitivity for detecting aortic dilation. While TTE identified some abnormalities, CT is crucial for accurate diagnosis.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Thoracic aortic screening is vital for early detection of aortic dilation.
- Clinical practice varies in tertiary centers regarding imaging modalities.
- Transthoracic echocardiography (TTE) and computed tomography (CT) are commonly used.
Purpose of the Study:
- To evaluate current thoracic aortic screening practices in a tertiary center.
- To compare the diagnostic value of TTE versus CT for aortic dilation.
- To identify additional cardiac and arterial abnormalities detected by each modality.
Main Methods:
- Retrospective analysis of 349 patients (≥15 years) undergoing thoracic aortic screening (2012-2016).
- Comparison of aortic diameters (sinus of Valsalva, ascending aorta) measured by TTE and CT.
- Assessment of TTE sensitivity and specificity for aortic dilation (≥40 mm) using CT as the reference standard.
Main Results:
- 65% of patients received both TTE and CT; 35% received TTE only.
- TTE showed lower sensitivity (57-61%) but high specificity (96-100%) for aortic dilation compared to CT.
- TTE detected cardiac abnormalities in 7% of patients; CT identified peripheral arterial issues in 4%.
Conclusions:
- Combined TTE and CT imaging is common practice.
- TTE has limited sensitivity for detecting thoracic aortic dilation.
- CT imaging is recommended at least once for comprehensive thoracic aortic screening.
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