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Published on: August 8, 2022
Robotic Transmitral Approach for Hypertrophic Cardiomyopathy With Systolic Anterior Motion
Nai-Kuan Chou1, Ryoi Okano1,2, Takeo Tedoriya2
1Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine.
Insights
A novel robotic transmitral approach offers a less invasive option for hypertrophic cardiomyopathy (HCM) patients. This technique effectively reduces outflow obstruction and mitral regurgitation (MR) with a single incision.
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Techniques
- Robotic Surgery
Background:
- Surgical intervention is indicated for symptomatic hypertrophic cardiomyopathy (HCM) patients with significant outflow obstruction.
- Traditional myectomy approaches (transapical, transaortic) are open procedures.
- A robotic transmitral approach offers a less invasive alternative using a single cardiac incision.
Purpose of the Study:
- To evaluate the feasibility and efficacy of a robotic transmitral approach for HCM.
- To compare outcomes with the standard transaortic approach.
- To assess the reduction of left ventricular outflow tract obstruction and mitral regurgitation (MR).
Main Methods:
- Retrospective analysis of 20 adult patients with obstructive HCM, severe MR, and systolic anterior motion (SAM).
- Comparison between 8 patients undergoing robotic transmitral myectomy and 12 patients undergoing standard transaortic myectomy.
- Analysis of pre- and post-operative pressure gradients, MR severity, ejection fraction, and operative times.
Main Results:
- Both groups showed similar pre-operative gradients, ejection fraction, and wall thickness.
- Post-operative MR was reduced to less than grade II in all patients.
- The robotic transmitral group demonstrated a significantly lower post-operative pressure gradient (1.5±2.6 mmHg vs. 10.6±10.8 mmHg, P=0.019) and shorter operation time (237.5±22.4 min vs. 309.6±28.5 min, P<0.01).
Conclusions:
- The robotic transmitral approach is a feasible and reliable method for treating HCM with SAM and MR.
- This minimally invasive technique effectively resolves septal hypertrophy and eliminates severe MR and SAM through a single atrial incision.
- Offers a promising alternative to open-chest procedures for selected HCM patients.
Background:
Surgical intervention is indicated in symptomatic hypertrophic cardiomyopathy (HCM) patients with a ventricular outflow pressure gradient more than 50 mmHg. The transmitral approach, along with the transapical and transaortic approaches, is routinely used for myectomy, but all are open procedures. We describe a robotic transmitral approach that can be used to resolve septal hypertrophied muscle and eliminate mitral regurgitation (MR) using 1 cardiac incision.
Methods And Results:
We retrospectively analyzed 20 adult patients with obstructive HCM who exhibited concomitant severe MR and systolic anterior motion (SAM). The 2 groups comprised 12 standard full-sternotomy transaortic and 8 robotic transmitral approaches. The pre-intraventricular pressure gradient was 69±14.2 mmHg in the robotic transmitral group and 70.2±17.4 mmHg in the transaortic group (P=0.876). Both groups had a similar left ventricular ejection fraction (65±8% vs. 72±9%, P=0.901) and maximal ventricular wall thickness (22.3±4.5 and 21.7±6.0, P=0.835). Postoperative MR was reduced to less than grade II in all patients. In the robotic group, the postoperative pressure gradient was 1.5±2.6 mmHg, which was lower than that of the transaortic group at 10.6±10.8 mmHg (P=0.019). The cross-clamp time was 95.3±7.7 min in the robotic group and 104.7±20.8 min in the transaortic group (P=0.193). The operation time was 237.5±22.4 and 309.6±28.5 min (P<0.01) in the robotic transmitral and transaortic groups, respectively.
Conclusions:
Using a robotic transmitral approach to treat with patients with HCM, SAM, and MR is feasible and reliable. Through 1 atrial incision, it is possible to resolve hypertrophy of the septum and eliminate both severe MR and SAM.
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