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Updated: Feb 4, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices
Published on: June 3, 2015
Microfluidic Thermally Activated Materials for Rapid Control of Macroscopic Compliance
Aditya Balasubramanian1, Mike Standish1, Christopher J Bettinger1,2,3
1Department of Materials Science and Engineering, Carnegie Mellon University, 5000 Forbes Avenue, WEH 3325, Pittsburgh, PA 15213-3890, USA.
Abstract:
Macroscopic structures that undergo rapid and reversible stiffness transitions can serve as functional polymeric materials for many applications in robotics and medical devices. Thermomechanical phase transitions can provide a suitable mechanism for transient control of mechanical properties. However, the characteristic time scale for actuation is large and dictated by the dimensions of the structure. Embedding vascular networks within bulk polymers can reduce the characteristic length scale of the material and permit rapid and reversible thermomechanical transitions. Here we report perfusable bulk materials with embedded microvascular networks that can undergo rapid and reversible stiffness transitions. Acrylate-based thermoplastic structures exhibit storage moduli with a dynamic range between E' = 1.02 ± 0.07 GPa and E' = 13.5 ± 0.7 MPa over time scales as small as 2.4 ± 0.5 s using an aqueous thermal perfusate. The spatiotemporal evolutions of temperature profiles were accurately predicted using finite element simulation and compared to experimental values. Rigid-compliant transitions were leveraged in a demonstration in which a microvascularized device was used to grasp an external object without the aid of moving parts.
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