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Updated: Feb 4, 2026

A Whole Cell Bioreporter Approach to Assess Transport and Bioavailability of Organic Contaminants in Water Unsaturated Systems
Published on: December 24, 2014
Bioformulative concepts on intracellular organ specific bioavailability
Nikhitha K Shanmukhan1, Arun Radhakrishnan1, Vinoth Maniarasan2
1Department of Pharmaceutics, JSS College of Pharmacy, Udagamund, JSS Academy of Higher Education & Research, Mysuru, India.
Abstract:
Bioavailability is an ancient but effective terminology by which the entire therapeutic efficacy of a drug directly or indirectly relays. Despite considering general plasma bioavailability, specific organ/tissue bioavailability will pave the path to broad spectrum dose calculation. Clear knowledge and calculative vision on bioavailability can improve the research and organ-targeting phenomenon. This article comprises a detailed introduction on bioavailability along with regulatory aspects, kinetic data and novel bioformulative approaches to achieve improved organ specific bioavailability, which may not be readily related to blood plasma bioavailability.
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