Physiological-based cord clamping in preterm infants using a new purpose-built resuscitation table: a feasibility...

Area of Science:

• Neonatal Medicine
• Perinatal Physiology
• Pediatric Resuscitation

Background:

• Physiological-based cord clamping (PBCC) demonstrates benefits in lambs but presents challenges in preterm infants.
• Previous studies highlight the need for effective stabilization techniques for premature neonates.

Purpose of the Study:

• To evaluate the feasibility of PBCC in preterm infants using a novel resuscitation table.
• To assess oxygen saturation (SpO2) and heart rate (HR) patterns during stabilization with PBCC.

Main Methods:

• An observational study was conducted at a tertiary referral center.
• Thirty-seven preterm infants (gestational age <35 weeks) were stabilized on the Concord resuscitation table.
• PBCC was initiated when infants met specific stability criteria (HR >100 bpm, spontaneous breathing, adequate SpO2).

Main Results:

• PBCC was successful in 89.2% of infants, with a median clamping time of 4:23 minutes.
• No adverse maternal or neonatal events were reported.
• Heart rate remained stable, and SpO2 levels increased significantly within 5 minutes, even with low fraction of inspired oxygen (FiO2).

Conclusions:

• PBCC is a feasible and safe method for preterm infants using the Concord resuscitation table.
• The technique supports stable cardiovascular adaptation and efficient oxygenation.
• This approach facilitates rapid improvement in SpO2 with minimal supplemental oxygen requirements.