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Published on: November 6, 2017
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Implementing the proclamation of stroke and potentially preventable dementias
Vladimir Hachinski1, Detlev Ganten2, Daniel Lackland3
1Department of Clinical Neurological Sciences, Western University, Ontario, Canada.
Journal of Clinical Hypertension (Greenwich, Conn.)
|October 10, 2018
Summary
Preventing stroke may also prevent dementia, as evidenced by population studies and atrial fibrillation treatment. Addressing shared risk factors like hypertension offers a joint prevention strategy for brain and heart health.
Area of Science:
- Neurology
- Public Health
- Cardiology
Background:
- Brain health is crucial for overall well-being and chronic disease management.
- Stroke and dementia are primary threats to brain health.
- Shared risk factors, particularly hypertension, link stroke, dementia, and heart disease.
Purpose of the Study:
- To explore the link between stroke prevention and dementia reduction.
- To highlight opportunities for joint prevention of cerebrovascular and cognitive disorders.
- To advocate for a unified approach to managing brain health.
Main Methods:
- Review of population studies on stroke and dementia incidence.
- Analysis of treatment outcomes for atrial fibrillation regarding stroke and dementia.
- Examination of early-stage Alzheimer disease pathology.
- Assessment of cognitive impairment in heart and kidney failure.
Main Results:
- A large population study indicated a 32% decrease in stroke and a 7% reduction in dementia.
- Atrial fibrillation treatment reduced stroke and dementia by 48%.
- Early Alzheimer disease shows vascular dysregulation.
- Cognitive impairment is associated with heart and kidney failure.
Conclusions:
- Preventing stroke shows potential for preventing certain dementias.
- Joint prevention of stroke, dementia, and heart disease is feasible by managing shared risk factors like hypertension.
- A global call for action promotes integrated strategies for brain health.
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