Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Predator-Prey Interactions02:39

Predator-Prey Interactions

21.6K
Predators consume prey for energy. Predators that acquire prey and prey that avoid predation both increase their chances of survival and reproduction (i.e., fitness). Routine predator-prey interactions elicit mutual adaptations that improve predator offenses, such as claws, teeth, and speed, as well as prey defenses, including crypsis, aposematism, and mimicry. Thus, predator-prey interactions resemble an evolutionary arms race.
21.6K
Dynamic Equilibrium02:20

Dynamic Equilibrium

62.7K
A reversible chemical reaction represents a chemical process that proceeds in both forward (left to right) and reverse (right to left) directions. When the rates of the forward and reverse reactions are equal, the concentrations of the reactant and product species remain constant over time and the system is at equilibrium. A special double arrow is used to emphasize the reversible nature of the reaction. The relative concentrations of reactants and products in equilibrium systems vary greatly;...
62.7K
Van der Waals Interactions01:24

Van der Waals Interactions

71.5K
Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.
71.5K
piRNA - Piwi-interacting RNAs02:57

piRNA - Piwi-interacting RNAs

7.7K
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
7.7K
Equation of Rotational Dynamics01:08

Equation of Rotational Dynamics

14.8K
Angular variables are introduced in rotational dynamics. Comparing the definitions of angular variables with the definitions of linear kinematic variables, it is seen that there is a mapping of the linear variables to the rotational ones. Linear displacement, velocity, and acceleration have their equivalents in rotational motion, which are angular displacement, angular velocity, and angular acceleration. Similar to the rotational variables, a mapping exists from Newton's second law of motion...
14.8K
Dynamics of Circular Motion01:30

Dynamics of Circular Motion

25.5K
An object undergoing circular motion, like a race car, is accelerating because it is changing the direction of its velocity. This centrally directed acceleration is called centripetal acceleration. This acceleration acts along the radius of the curved path (thus is also referred to as radial acceleration).
Any acceleration must be produced by some force. Therefore, any force or combination of forces can cause centripetal acceleration. A few examples include the tension in the rope on a...
25.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metabolic Glycoengineering of Synthetic "Membrane Receptors" via Supramolecular Host-Guest Recognition.

Bioconjugate chemistry·2026
Same author

Engineering a Glucose-Responsive Glucagon Prodrug Through Arginine-Phenylboronic Acid Pendant Modification.

Small science·2026
Same author

Chitosan-Glycerol Injectable Hydrogel for Intratumoral Delivery of Macromolecules.

Gels (Basel, Switzerland)·2025
Same author

Mechanoresponsive Hydrogels Emerging from Dynamic and Non-Covalent Interactions.

Advanced materials (Deerfield Beach, Fla.)·2025
Same author

Programmable Host-Guest Recognition for Shape-Shifting Supramolecular Nanostructure States.

ACS nano·2025
Same author

Mechanistic Insights for Glucose-Driven Coacervation of a Supramolecular Peptide and Therapeutic Protein.

ACS applied materials & interfaces·2025
Same journal

AI-Derived Smart Microneedle Systems for Advanced Wound Management: From Intelligent Sensing to Closed-Loop Therapy.

Macromolecular bioscience·2026
Same journal

A Novel Chitosan-Gelatin Scaffold and Cell Spray Therapy for Treating Limbal Stem Cell Deficiency.

Macromolecular bioscience·2026
Same journal

Electroconductive Soft Microcarriers for Suspension Culture of Skeletal Muscle Cells.

Macromolecular bioscience·2026
Same journal

Dual-Responsive Chitosan-Grafted PNIPAAm Hydrogel Eye Drop Incorporating Insulin-Imprinted Microgels for Dry Eye Syndrome Treatment.

Macromolecular bioscience·2026
Same journal

Levan Inspired Hybrid Composites Materials: Bridging Natural Polysaccharides with Biomedical Technology.

Macromolecular bioscience·2026
Same journal

Anion-Specific Mechanisms in Fibrinogen Self-Assembly: Contrasting Effects of Phosphates and Chlorides in Nanofiber Formation.

Macromolecular bioscience·2026
See all related articles

Related Experiment Video

Updated: Feb 4, 2026

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
10:39

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction

Published on: August 23, 2018

8.3K

Dynamic Hydrogels from Host-Guest Supramolecular Interactions.

Siena M Mantooth1, Brizzia G Munoz-Robles1, Matthew J Webber1

  • 1Department of Chemical and Biomolecular Engineering, University of Notre Dame, 205 McCourtney Hall, Notre Dame, IN, 46556, USA.

Macromolecular Bioscience
|October 11, 2018
PubMed
Summary
This summary is machine-generated.

Host-guest supramolecular hydrogels utilize host-guest interactions for physical cross-linking. These dynamic biomaterials offer tunable properties for diverse biomedical applications.

Keywords:
drug deliveryinjectable biomaterialsmaterials chemistryrheology

More Related Videos

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.9K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.9K

Related Experiment Videos

Last Updated: Feb 4, 2026

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
10:39

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction

Published on: August 23, 2018

8.3K
An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.9K
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

8.9K

Area of Science:

  • Biomaterials Science
  • Supramolecular Chemistry
  • Polymer Science

Background:

  • Hydrogel biomaterials are widely used in medicine, including contact lenses, drug delivery, and cell scaffolding.
  • A specific class of hydrogels relies on physical cross-linking via host-guest interactions.

Purpose of the Study:

  • To explore the preparation and properties of host-guest supramolecular hydrogels.
  • To highlight the potential of these dynamic materials in biomedical applications.

Main Methods:

  • Utilizing host macrocycles and guest molecules to form non-covalent cross-links in polymer chains.
  • Investigating the formation of poly(pseudo)rotaxanes for enhanced physical cross-linking.
  • Characterizing the dynamic properties and responsiveness of the resulting hydrogels.

Main Results:

  • Successfully prepared hydrogels through host-guest complexation and poly(pseudo)rotaxane formation.
  • Demonstrated that non-covalent interactions and polymer jamming contribute to physical cross-linking.
  • Showcased the tunable and responsive nature of these supramolecular hydrogels.

Conclusions:

  • Host-guest supramolecular hydrogels represent a promising new class of biomaterials.
  • Their dynamic properties and responsiveness stem from non-covalent supramolecular interactions.
  • These hydrogels are suitable for a variety of advanced biomedical applications.