Related Experiment Video
Updated: Feb 4, 2026

Potato Virus X-Based microRNA Silencing VbMS In Potato.
Published on: May 11, 2020
Isolation and structural characterization of a non-diketopiperazine phytotoxin from a potato pathogenic Streptomyces
María Inés Lapaz1, Andrés López2, José Carlos Huguet-Tapia3
1a Área Microbiología, Departamento de Biociencias, Facultad de Química, UdelaR , Montevideo , Uruguay.
Abstract:
Two Streptomyces spp. strains responsible for potato common scab infections in Uruguay which do not produce diketopiperazines were identified through whole-genome sequencing, and the virulence factor produced by one of them was isolated and characterized. Phylogenetic analysis showed that both pathogenic strains can be identified as S. niveiscabiei, and the structure of the phytotoxin was elucidated as that of the polyketide desmethylmensacarcin using MS and NMR methods. The metabolite is produced in yields of ∼200 mg/L of culture media, induces deep necrotic lesions on potato tubers, stuns root and shoot growth in radish seedlings, and is comparatively more aggressive than thaxtomin A. This is the first time that desmethylmensacarcin, a member of a class of compounds known for their antitumor and antibiotic activity, is associated with phytotoxicity. More importantly, it represents the discovery of a new virulence factor related to potato common scab, an economically-important disease affecting potato production worldwide.
Related Concept Videos
Thermal Strain
Shearing Strain
Measurements of Strain
Strain Energy
Consider a rod that is fixed at one end and subjected to an axial force at the free end. This axial force induces stress within the rod, leading to its elongation. As the axial force increases, so does the elongation of the rod, illustrating a direct relationship between the force applied and the resulting...
Problem Solving on Stress and Strain
Stress-Strain Diagram

