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A Practical Guide to Whole Slide Imaging: A White Paper From the Digital Pathology Association
Mark D Zarella1, Douglas Bowman1, Famke Aeffner1
1From the Department of Pathology & Laboratory Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania (Drs Zarella and Absar); Pharma Services, Indica Labs, Inc, Corrales, New Mexico (Mr Bowman); Comparative Biology and Safety Sciences, Amgen, Inc, South San Francisco, California (Dr Aeffner); 3Scan, San Francisco, California (Dr Farahani); Barco, Inc, Beaverton, Oregon (Mr Xthona); the Department of Pathology, The Ohio State University, Columbus (Dr Parwani); the Department of Anatomic Pathology, H. Lee Moffitt Cancer Center, Tampa, Florida (Dr Bui); and the Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dr Hartman).
Whole slide imaging (WSI) digitizes glass slides, revolutionizing pathology workflows and collaboration. Overcoming implementation challenges is key to widespread adoption of this transformative technology.
Area of Science:
- Digital Pathology
- Medical Imaging
- Pathology Informatics
Background:
- Whole slide imaging (WSI) digitizes glass slides, enabling a new era of digital pathology tools.
- WSI significantly impacts pathology workflows, education, research, and collaboration.
- Despite benefits, WSI implementation faces adoption barriers, particularly regarding technological understanding and perceived reimbursement.
Purpose of the Study:
- To provide an overview of current and future Whole Slide Imaging (WSI) technology.
- To highlight immediate applications of WSI in pathology practice, education, research, and collaboration.
Main Methods:
- A review of peer-reviewed literature.
- Expert insights from pathologists, scientists, and technologists with practical WSI experience.
Main Results:
- Whole slide imaging (WSI) offers substantial benefits for pathology practices, academic centers, and research institutions.
- Regulatory clearance in the US has reduced some adoption barriers.
- Implementation remains complex, requiring multidisciplinary input and clear communication of benefits.
Conclusions:
- Successful WSI implementation is a multidisciplinary effort involving pathologists, technologists, and leadership.
- Understanding implementation challenges, benefits, and successes is crucial for prospective users.
- Strategic planning and stakeholder education are vital for overcoming WSI adoption hurdles.
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