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Martina Schriber1, Valerie G. A. Suter1

  • 1Klinik für Oralchirurgie und Stomatologie, Zahnmedizinische Kliniken der Universität Bern

Swiss Dental Journal
|October 13, 2018
PubMed
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Erythema exsudativum multiforme (EEM) is an acute inflammatory condition affecting skin and mucous membranes, often starting on the lips. Diagnosis is typically based on clinical presentation, avoiding the need for biopsies.

Area of Science:

  • Dermatology
  • Oral Medicine
  • Inflammatory Diseases

Background:

  • Erythema exsudativum multiforme (EEM) presents as acute inflammation of skin and/or mucous membranes.
  • It commonly affects young, healthy males, frequently involving the lips initially.
  • Intraoral lesions can extend to the palate and floor of the mouth, causing significant discomfort.

Purpose of the Study:

  • To describe the clinical presentation and diagnostic approach for Erythema exsudativum multiforme.
  • To highlight the typical patient demographic and common sites of EEM manifestation.
  • To emphasize the diagnostic sufficiency of clinical examination in EEM cases.

Main Methods:

  • Clinical observation and case review of patients diagnosed with EEM.
  • Analysis of lesion distribution, patient demographics, and reported symptoms.
Keywords:
Erythema exsudativum multiformeStevens-Johnson-Syndromarzneimittelinduzierte Erkrankung

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  • Evaluation of diagnostic criteria, including the role of histopathology.

    • Main Results:

    • EEM predominantly affects young males, with initial or exclusive lip involvement.
    • Oral lesions include buccal mucosa, gingiva, tongue, palate, and floor of the mouth.
    • Severe pain during eating, swallowing, and speaking is a common symptom.

    Conclusions:

    • The clinical presentation of EEM is often distinctive enough for diagnosis.
    • Histopathological examination is generally not required for diagnosing EEM.
    • Early recognition of EEM is crucial for managing patient discomfort and symptoms.