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The Dynamic Duo: Combining noninvasive brain stimulation with cognitive interventions
Aakash V Sathappan1, Bruce M Luber1, Sarah H Lisanby1
1Noninvasive Neuromodulation Unit, Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Progress in Neuro-Psychopharmacology & Biological Psychiatry
|October 13, 2018
Summary
Combining non-invasive brain stimulation (NIBS) with cognitive interventions shows promise for treating psychiatric disorders. This approach may enhance neural activity control for more effective mental health care.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Science
Background:
- Pharmacotherapy and psychotherapy are standard psychiatric treatments, but unmet needs persist.
- Non-invasive brain stimulation (NIBS) is an emerging therapeutic modality.
- Combination therapies are increasingly explored for synergistic effects.
Purpose of the Study:
- To review evidence for combining NIBS with cognitive interventions for neuropsychiatric disorders.
- To explore the potential of transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) in combination therapies.
- To discuss underlying mechanisms and future research directions.
Main Methods:
- Review of existing literature on NIBS (tDCS, TMS) combined with cognitive interventions.
- Focus on state-dependent effects of NIBS and optimizing therapy through cognitive control.
- Examination of studies across major depressive disorder, schizophrenia, generalized anxiety, and autism.
Main Results:
- Evidence suggests NIBS combined with cognitive interventions can be a powerful therapeutic approach.
- Simultaneous or sequential cognitive interventions may optimize NIBS by controlling neural activity.
- The review highlights potential for treating a range of neuropsychiatric conditions.
Conclusions:
- Combination therapy of NIBS and cognitive interventions offers a promising new avenue for psychiatric treatment.
- Understanding state-dependent effects is key to optimizing this multi-modal approach.
- Further research is needed to refine mechanisms and therapeutic strategies.
Keywords:
Cognitive interventionsNon-invasive brain stimulationSynergistic mechanismsTranscranial direct current stimulationTranscranial magnetic stimulationMore Related Videos
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