Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

59.9K
Overview
59.9K
Urologic Endoscopic Procedure: Cystoscopic Examination01:28

Urologic Endoscopic Procedure: Cystoscopic Examination

3.0K
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
3.0K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

1.5K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.5K
Continuing Care01:25

Continuing Care

2.0K
Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
2.0K
Continuity of a Function01:23

Continuity of a Function

241
A function is continuous at a point a if three conditions are met: the function is defined at a, the limit of the function as x approaches a exists, and this limit equals the function’s value. Mathematically, this is written asThis definition ensures the graph of the function does not exhibit any breaks, holes, or jumps at that point. Discontinuities occur when any of these conditions fail. A removable discontinuity exists when the two-sided limit exists but the function is either...
241
Continuity Equation01:28

Continuity Equation

3.3K
The continuity equation asserts that the mass flow rate must remain constant for a steady flow of an incompressible fluid within a confined system. This principle applies to systems where fluid passes through varying cross-sectional areas, such as nozzles, syringes, and pipes.
The mass flow rate is expressed as:
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Standardizing terminology and management of testicular developmental disorders: A comprehensive review and international expert consensus.

Journal of pediatric urology·2026
Same author

Journal of Pediatric Urology Editorial Board policy statement on appropriate endpoints when conducting research on hydronephrosis/urinary tract dilation (UTD)/ureteropelvic junction obstruction (UPJO).

Journal of pediatric urology·2026
Same author

Does vesicoureteral reflux severity impact breakthrough UTI risk: a multi-institutional analysis and risk stratification.

World journal of urology·2026
Same author

Response to Letter to the Editor re: "Predicting non-response to urotherapy in pediatric bowel and bladder dysfunction: A machine learning approach".

Journal of pediatric urology·2026
Same author

Response to Letter to the Editor re: "Motivating peer review: Why the peer review process is an essential part of our professional development".

Journal of pediatric urology·2026
Same author

Response to Letter to the Editor re: "Education and training in hypospadias surgery: Current status, competency assessment, and the role of modern educational tools".

Journal of pediatric urology·2026

Related Experiment Video

Updated: Feb 4, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.5K

Continuous Antibiotic Prophylaxis in Pediatric Urology.

Douglas W Storm1, Luis H Braga2, Christopher S Cooper1

  • 1Department of Urology, University of Iowa, Carver College of Medicine, 200 Hawkins Drive, 3RCP, Iowa City, IA 5224, USA.

The Urologic Clinics of North America
|October 15, 2018
PubMed
Summary

Continuous antibiotic prophylaxis (CAP) can be used selectively in children with urinary tract issues. This approach identifies patients most likely to benefit, considering risks like antibiotic resistance and microbiome impact.

Keywords:
Antibiotic prophylaxisAntibiotic resistanceMegaureterMicrobiotaPrenatal hydronephrosisSide effectsVesicoureteral reflux

More Related Videos

Antibiotic Dereplication Using the Antibiotic Resistance Platform
10:49

Antibiotic Dereplication Using the Antibiotic Resistance Platform

Published on: October 17, 2019

11.7K
Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
03:37

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

Published on: June 6, 2025

468

Related Experiment Videos

Last Updated: Feb 4, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.5K
Antibiotic Dereplication Using the Antibiotic Resistance Platform
10:49

Antibiotic Dereplication Using the Antibiotic Resistance Platform

Published on: October 17, 2019

11.7K
Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
03:37

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

Published on: June 6, 2025

468

Area of Science:

  • Pediatric Nephrology
  • Infectious Diseases
  • Pharmacology

Background:

  • Urinary tract infections (UTIs) are common in children with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis.
  • Continuous antibiotic prophylaxis (CAP) is a common strategy for UTI prevention in these pediatric patients.
  • Concerns exist regarding the long-term effects of CAP, including antibiotic resistance and microbiome disruption.

Purpose of the Study:

  • To review the current evidence for continuous antibiotic prophylaxis (CAP) in children with specific urinary tract abnormalities.
  • To advocate for a more selective approach to CAP based on individual risk factors.
  • To explore potential side effects and alternatives to CAP.

Main Methods:

  • Systematic review of existing literature on CAP for pediatric UTIs.
  • Analysis of individual risk factors associated with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis.
  • Evaluation of short-term and long-term side effects of CAP, including impact on bacterial resistance and the microbiome.
  • Review of alternative prophylactic strategies.

Main Results:

  • A selective use of CAP is recommended, targeting children with identifiable risk factors for UTI.
  • Potential adverse effects of CAP include increased bacterial resistance and negative impacts on the gut microbiome.
  • Alternative strategies such as Vaccinium macrocarpon, probiotics, and vaccines show promise.

Conclusions:

  • Selective use of CAP can optimize treatment benefits while minimizing risks in children with urinary tract conditions.
  • Further research is needed to validate alternative prophylactic measures and understand long-term outcomes.
  • Personalized risk assessment is crucial for guiding CAP decisions in pediatric urology.