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Updated: Feb 3, 2026

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections
Published on: October 31, 2017
[Sexually Transmitted Infections in the Tropics].
1Department of Dermatology, Preah Kossamak-Hospital, BP 1006, Phnom Penh, Kambodscha. cambodia.derma@gmail.com.
Sexually transmitted infections (STIs) are a global health issue, with tropical STIs like chancroid, lymphogranuloma venereum, and granuloma inguinale posing significant risks. Prevention involves safe sex practices and condom use to reduce transmission.
Area of Science:
- Tropical Medicine
- Infectious Diseases
- Public Health
Background:
- Sexually transmitted infections (STIs) are globally prevalent, with an estimated 500 million cases annually for chlamydia, gonorrhea, syphilis, and trichomoniasis.
- 75% of these infections occur in tropical regions, including Latin America, sub-Saharan Africa, and South/Southeast Asia.
- Bacterial tropical STIs include chancroid, lymphogranuloma venereum (LGV), and granuloma inguinale (GI, also known as Donovanosis).
Purpose of the Study:
- To define and discuss bacterial tropical STIs.
- To highlight the geographical distribution and associated risk factors of these infections.
- To emphasize the link between tropical STIs, skin ulcerations, and increased HIV/STI transmission risk.
Main Methods:
- Literature review and synthesis of epidemiological data on STIs.
- Focus on specific bacterial infections prevalent in tropical zones.
- Analysis of risk factors, including climate, socioeconomic status, and sexual practices.
Main Results:
- Tropical STIs are concentrated in equatorial regions (between 23.5° N and S latitudes) characterized by hot, humid climates, poverty, and underdevelopment.
- Chancroid, LGV, and GI are primarily associated with skin ulcerations.
- Skin ulcerations significantly increase the risk of HIV and other STI transmission.
Conclusions:
- Tropical STIs represent a distinct and significant public health challenge in specific geographical areas.
- The presence of skin ulcerations due to these infections exacerbates HIV/STI epidemics.
- Minimizing the risk of tropical STIs requires avoiding high-risk sexual behaviors and consistent condom use.
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