Related Experiment Video
Updated: Feb 3, 2026
Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Use of Chlorhexidine to Prevent Ventilator-Associated Pneumonia in a Long-term Care Setting: A Retrospective Medical
Margaret K McCue1, Glen A Palmer
1St Cloud VA Health Care System, St Cloud, Minnesota.
Background:
The purpose of this study was to explore the use of the oral decontamination solution chlorhexidine (CHX) to reduce ventilator-associated pneumonia (VAP) in a long-term ventilator care setting over time. Most of the research in this area has been conducted in acute and intensive care settings.
Methods:
This study was a retrospective medical record review conducted in a long-term care facility with a dedicated ventilator unit. Veterans records (N = 12) were accessed for this study. The study covered 50 months, with a 43-month time period during which CHX was administered.
Results:
While the sample size was small, many of the veterans on ventilators used CHX for years without an incident of VAP.
Conclusions:
These findings support using CHX to significantly reduce the number of days of intravenous antibiotics used to treat VAP with little side effects.
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