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Inflammation after Stroke: A Local Rather Than Systemic Response?

Ruslan Rust1, Lisa Grönnert2, Martin E Schwab3

  • 1Institute for Regenerative Medicine, University of Zurich, Zurich, Switzerland; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland; These authors contributed equally to this work.

Trends in Neurosciences
|October 18, 2018
PubMed

After injury, activation and recruitment of inflammatory and immune cells has been thought to occur throughout the whole body. A recent study shows that after brain injury in mice, immune cells are primarily recruited from nearby skull bone marrow and invade the brain through microscopic vascular channels. Manipulation of this process may provide new therapeutic options.

Keywords:
immune cell recruitmentischemianeutrophilsvascular channels

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