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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

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The prediction of preterm delivery: What is new?

Natalie Suff1, Lisa Story2, Andrew Shennan1

  • 1Department of Women's Health, King's College London, St Thomas' Hospital, London, UK.

Seminars in Fetal & Neonatal Medicine
|October 20, 2018
PubMed

Insights

Predicting preterm birth (delivery before 37 weeks) is vital for maternal and infant health. Combining multiple tests shows promise for improving early detection and guiding interventions for high-risk pregnancies.

Area of Science:

  • Obstetrics and Gynecology
  • Perinatology
  • Neonatal Medicine

Background:

  • Preterm birth affects 11% of global pregnancies, causing significant neonatal morbidity and mortality.
  • Accurate prediction of preterm birth is crucial for timely interventions and improved antenatal management.
  • Current predictive tests have limitations, necessitating exploration of combined and novel approaches.

Purpose of the Study:

  • To review the clinical utility of currently marketed preterm birth predictive tests.
  • To discuss novel predictive tests for preterm birth.
  • To evaluate these tests in both singleton and multiple pregnancies.

Main Methods:

  • Systematic review of existing literature on preterm birth prediction.
  • Analysis of the clinical utility of marketed predictive tests.
  • Exploration of emerging predictive technologies and biomarkers.

Main Results:

  • No single test is currently sufficient for accurate preterm birth prediction.
  • A combination of tests is likely to enhance clinical prediction accuracy.
  • Future novel tests may offer improved predictive capabilities.

Conclusions:

  • Improving preterm birth prediction is essential for reducing adverse neonatal outcomes.
  • Combined testing strategies offer a promising avenue for enhanced clinical prediction.
  • Continued research into novel predictive markers is warranted for future clinical application.

Keywords:
BiomarkersCervical lengthMultiple pregnanciesPrediction testsPremature birth

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