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Glutathione as a Marker for Human Disease
Garrett Teskey1, Rachel Abrahem1, Ruoqiong Cao2
1Graduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Advances in Clinical Chemistry
|October 22, 2018
Summary
Glutathione (GSH), a master antioxidant, is vital for cellular health. Its imbalance is linked to diseases like cancer and aging, suggesting GSH
Area of Science:
- Biochemistry
- Cellular Biology
- Medical Research
Background:
- Glutathione (GSH) is a critical endogenous antioxidant.
- GSH plays a role in numerous metabolic processes.
- GSH deficiency is linked to cellular oxidative damage.
Purpose of the Study:
- To discuss the role of Glutathione (GSH) in various pathological conditions.
- To highlight the potential of GSH as a biomarker for human diseases.
Main Methods:
- Literature review and synthesis of existing research on GSH.
- Analysis of GSH's involvement in diseases such as tuberculosis, HIV, diabetes, cancer, and aging.
Main Results:
- GSH imbalance is a common feature across diverse pathological conditions.
- GSH's multifaceted roles underscore its importance in maintaining cellular integrity.
Conclusions:
- Glutathione (GSH) imbalance is a significant indicator in multiple diseases.
- GSH serves as a potential biomarker for diagnosing and monitoring human diseases.
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