Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Understanding the Self01:28

Understanding the Self

295
The self is a central aspect of human identity, encompassing an individual’s beliefs, emotions, perceptions, and experiences. It is a cognitive and psychological construct that enables individuals to interpret their traits and behaviors, influencing how they perceive themselves and interact with the world. While personality consists of stable and enduring characteristics, the self is shaped by self-perception and social experiences. This distinction highlights the dynamic nature of the...
295
Understanding Self-Concept01:20

Understanding Self-Concept

280
The self-concept encompasses individuals' beliefs about themselves, structured through cognitive frameworks known as self-schemas. These schemas function as mental representations of specific traits or behaviors, influencing how self-relevant information is perceived, processed, and remembered. For example, individuals who are schematic for body weight are more likely to interpret routine experiences—such as dining out or shopping—through the lens of that trait. Conversely, those...
280
Understanding Deception01:14

Understanding Deception

168
Deception is a pervasive aspect of human communication. Empirical studies have shown that most individuals engage in some form of deceit on a daily basis, with approximately 20% of social exchanges involving deceptive elements. Lying follows a developmental trajectory, peaking during adolescence and declining with age, possibly due to the maturation of cognitive control and social accountability.Cognitive and Social Factors in Deception DetectionDespite its prevalence, accurately detecting...
168
What is the Immune System?01:38

What is the Immune System?

128.1K
Overview
128.1K
Understanding Love01:27

Understanding Love

189
Love, as a multifaceted psychological construct, encompasses emotions, cognitive processes, and behavioral patterns that play a crucial role in human relationships. It extends beyond attraction, manifesting in deep, enduring connections that influence personal well-being and social structures.Psychological Dimensions of LoveLove differs from friendship and mere liking through its depth and intensity. While friendship is built on mutual respect, trust, and companionship, love involves emotional...
189
Understanding Consciousness01:23

Understanding Consciousness

2.1K
Consciousness can be defined as the state of being aware of and able to think about one's existence, sensations, and surroundings. It encompasses two major components: awareness and arousal. Awareness pertains to the recognition of environmental stimuli and internal states. At the same time, arousal refers to the physiological readiness to engage with these stimuli, which varies significantly between states like sleep and wakefulness.
Sleep, a crucial state, is characterized by reduced...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immune function and dysfunction are determined by lymphoid tissue efficacy.

Disease models & mechanisms·2022
Same author

Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice.

PLoS pathogens·2018
Same author

Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics.

PloS one·2017
Same author

Effect of fluticasone propionate on virus-induced airways inflammation and anti-viral immune responses in mice.

Lancet (London, England)·2015
Same author

Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK).

Thorax·2015
Same author

LTB4 increases nasal neutrophil activity and conditions neutrophils to exert antiviral effects.

Respiratory medicine·2011

Related Experiment Video

Updated: Feb 3, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.5K

Recent advances in understanding rhinovirus immunity.

Spyridon Makris1, Sebastian Johnston1

  • 1National Heart and Lung Institute, Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, UK.

F1000Research
|October 23, 2018
PubMed
Summary

Rhinoviruses cause common colds but can worsen asthma and COPD. Understanding immune responses, particularly Th1 vs. Th2, is key to developing treatments for rhinovirus infections and related exacerbations.

Keywords:
AsthmaRhinoviruses

More Related Videos

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
08:32

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors

Published on: June 7, 2018

10.4K
Understanding Cerebellar Pattern Formation
13:18

Understanding Cerebellar Pattern Formation

Published on: November 1, 2007

5.5K

Related Experiment Videos

Last Updated: Feb 3, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.5K
Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
08:32

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors

Published on: June 7, 2018

10.4K
Understanding Cerebellar Pattern Formation
13:18

Understanding Cerebellar Pattern Formation

Published on: November 1, 2007

5.5K

Area of Science:

  • Immunology
  • Virology
  • Respiratory Medicine

Background:

  • Rhinoviruses are the primary cause of upper respiratory infections.
  • They can trigger severe lower respiratory tract infections and exacerbate conditions like asthma and COPD.
  • Antigenic diversity of over 160 rhinovirus strains hinders vaccine development.

Purpose of the Study:

  • To review recent advancements in understanding immunity to rhinovirus infection.
  • To explore how innate and adaptive immune responses contribute to rhinovirus-induced asthma exacerbations.

Main Methods:

  • This commentary synthesizes current research on rhinovirus immunology.
  • Focuses on the role of immune response phenotypes (Th1/Th2) and cellular components (neutrophilia).

Main Results:

  • Healthy individuals typically mount a T helper type 1 (Th1) immune response to rhinoviruses.
  • Asthma exacerbations linked to rhinovirus involve an amplified Th2 response and airway neutrophilia.
  • Balanced innate immune responses are crucial for mitigating rhinovirus-induced illness.

Conclusions:

  • Immune response phenotype significantly influences rhinovirus disease severity.
  • Targeting immune responses, particularly the Th2 bias and neutrophilia in asthma, may offer therapeutic strategies.
  • Further research into rhinovirus immunity is essential for improved prevention and treatment.