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Related Concept Videos

Lewis Acids and Bases02:33

Lewis Acids and Bases

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In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
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Base Excision Repair01:54

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One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
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Weak Base Solutions03:21

Weak Base Solutions

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Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
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Ions as Acids and Bases02:54

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Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
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DNA Base Pairing02:27

DNA Base Pairing

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Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
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Bronsted-Lowry Acids and Bases02:58

Bronsted-Lowry Acids and Bases

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The acid-base reaction class has been studied for quite some time. In 1680, Robert Boyle reported traits of acid solutions that included their ability to dissolve many substances, to change the colors of certain natural dyes, and to lose these traits after coming in contact with alkali (base) solutions. In the eighteenth century, it was recognized that acids have a sour taste, react with limestone to liberate a gaseous substance (now known to be CO2), and interact with alkalis to form neutral...
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Digital Microfluidics for Automated Proteomic Processing
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Microfluidics-Based Biomaterials and Biodevices.

Ruihua Dong1,2, Yong Liu1,3, Lei Mou1,3

  • 1Beijing Engineering Research Center for BioNanotechnology and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.

Advanced Materials (Deerfield Beach, Fla.)
|October 23, 2018
PubMed
Summary
This summary is machine-generated.

Microfluidics technology drives innovation in biomaterials and biodevices for healthcare. This review covers advances in functional biomaterials, cell manipulation, and flexible biodevices, outlining future trends.

Keywords:
biomaterialscell manipulationsflexible biodeviceshuman healthcaremicrofluidics

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Area of Science:

  • Biomaterials Science
  • Microfluidics
  • Bioengineering

Background:

  • Microfluidics technology enables precise control over fluids and cells at the microscale.
  • This precision is crucial for advancements in materials science, especially in biological applications.
  • Interactions between microfluidics and biological systems are rapidly evolving.

Purpose of the Study:

  • To review the latest advancements in microfluidics-based biomaterials and biodevices.
  • To highlight key emerging areas: functional biomaterials, cell manipulations, and flexible biodevices.
  • To discuss the interconnectedness of these areas and their unified goal in human healthcare.

Main Methods:

  • Literature review of recent research in microfluidics for biomaterials and biodevices.
  • Analysis of studies focusing on functional biomaterials, cell manipulation techniques, and flexible biodevices.
  • Synthesis of findings to identify common principles and future directions.

Main Results:

  • Microfluidics enables precise control over material composition and morphology.
  • Significant progress has been made in developing functional biomaterials and advanced cell manipulation techniques.
  • Flexible biodevices leveraging microfluidics show great promise for healthcare applications.

Conclusions:

  • Microfluidics is a key enabling technology for next-generation biomaterials and biodevices.
  • Continued research in microfluidics will accelerate innovations in human healthcare.
  • Addressing current challenges will pave the way for future development trends in biological applications.