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Implementing core outcomes in kidney disease: report of the Standardized Outcomes in Nephrology (SONG) implementation

Allison Tong1, Braden Manns2, Angela Yee Moon Wang3

  • 1The University of Sydney School of Public Health, Sydney, New South Wales, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.

Kidney International
|October 27, 2018
PubMed

Insights

Standardized Outcomes in Nephrology (SONG) identified core outcomes critical for patients and professionals in chronic kidney disease trials. Implementation strategies were discussed to ensure consistent reporting and improve patient-important outcomes.

Area of Science:

  • Nephrology
  • Clinical Trials
  • Patient-Reported Outcomes

Background:

  • Chronic kidney disease research features numerous trials, but often prioritizes biochemical markers over patient-centered outcomes like cardiovascular disease, mortality, and quality of life.
  • Outcome heterogeneity in kidney disease trials limits their impact on clinical practice and health policy.
  • The Standardized Outcomes in Nephrology (SONG) Initiative aims to establish consensus on core outcomes vital for patients and clinicians.

Framework:

  • The SONG Initiative focuses on identifying and promoting the consistent reporting of patient-important outcomes in nephrology research.
  • Core outcomes are defined as those critically important to patients and health professionals.

Implementation:

  • A SONG Implementation Workshop convened 82 patients, caregivers, and health professionals to discuss core outcome implementation.
  • Key themes included socializing the concept of core outcomes and demonstrating their feasibility and usability in trials.
  • Strategies for stakeholder partnership were outlined to enhance acceptance and reporting.

Implications:

  • Successful implementation of core outcomes can improve the relevance and impact of chronic kidney disease trials.
  • Consistent reporting of patient-important outcomes can inform guideline development and health policy.
  • Adoption of SONG recommendations may lead to better patient outcomes in nephrology.
Keywords:
core outcome setsimplementationkidney diseaseoutcomespatient-centered caretrials

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