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Viral Recombination

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Viral Structure

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Size and Structure of Viral Genomes

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Immune Response Against Viral Pathogens

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Updated: Feb 3, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Viral Encephalitis.

Arun Venkatesan¹, Olwen C Murphy¹

¹Division of Neuroimmunology and Neuroinfectious Diseases, Department of Neurology, Johns Hopkins Encephalitis Center, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA.

Neurologic Clinics

|October 28, 2018

Summary

This summary is machine-generated.

Viral infections frequently cause encephalitis, a serious brain inflammation. Identifying the specific virus through diagnostic tests is crucial for effective treatment and management.

Keywords:

Acute disseminated encephalomyelitis Autoimmune encephalitis Encephalitis Herpes simplex encephalitis Infectious encephalitis NMDAR encephalitis Viral encephalitis

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Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins

Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins

Published on: August 31, 2017

Area of Science:

Neurology
Infectious Diseases
Virology

Background:

Encephalitis is a significant cause of central nervous system inflammation.
Viruses are a primary etiology of encephalitis, with numerous viral agents implicated.

Purpose of the Study:

To outline the common and important viral causes of encephalitis.
To emphasize the role of host factors and clinical presentation in diagnosis.
To highlight key diagnostic modalities and the importance of considering treatable forms.

Main Methods:

Review of common and important viral pathogens associated with encephalitis.
Discussion of diagnostic approaches including cerebrospinal fluid analysis, serology, PCR, and neuroimaging.
Consideration of postinfectious autoimmune conditions mimicking viral encephalitis.

Main Results:

Herpesviruses, arboviruses, enteroviruses, and others are frequent viral culprits.
Clinical features and host factors guide the etiological investigation.
Diagnostic tools like CSF analysis, serology, PCR, and neuroimaging are essential.
Postinfectious autoimmune processes can also lead to CNS inflammation.

Conclusions:

Prompt and accurate diagnosis of viral encephalitis is critical.
A comprehensive diagnostic strategy incorporating clinical, laboratory, and imaging data is necessary.
Recognition of treatable causes and autoimmune mimics is vital for patient outcomes.