Related Experiment Video
Updated: Feb 3, 2026

Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
Published on: May 6, 2014
Anticonvulsants as monotherapy or adjuncts to treat alcohol withdrawal: A systematic review
Aarti Chhatlani, Syeda Arshiya Farheen, Geetha Manikkara
1Chairman, Department of Psychiatry and Behavioral Sciences, Cleveland Clinic Akron General, Akron, Ohio 44307 USA;
Background:
This systematic review evaluates current literature on anticonvulsants to treat alcohol withdrawal symptoms (AWS).
Methods:
We performed a literature search of PubMed, MEDLINE, PsycINFO, EMBASE, and Cochrane collaboration databases through September 30, 2016. The search was not restricted by patients' age. Articles published in English or with official English translations were included.
Results:
We found 16 double-blind randomized controlled trials (RCTs) that evaluated the use of anticonvulsants as treatment of AWS. Available data indicates that anticonvulsants are as effective as sedatives/hypnotics in treating mild or moderate AWS. Two studies evaluated the use of anticonvulsants as adjuncts. Combining anticonvulsants with sedatives decreases the quantity of sedatives required and AWS may resolve quicker. There is some data that anticonvulsants can be used to treat AWS as monotherapy. Fourteen of these studies assessed adverse effects of these medications; 13 studies identified minor adverse effects and one found the adverse effects to be intolerable.
Conclusions:
Available evidence indicates that anticonvulsants have good efficacy as monotherapy and as adjuncts with sedatives/hypnotics in treating mild to moderate AWS.
More Related Videos
Related Concept Videos
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Heart Failure VI: Adjunct Therapies
Random and Systematic Errors
Systematic Sampling Method
Systematic sampling is one of the simplest methods...
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:

