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Applying emerging technologies to improve diabetes treatment
Yu Jiaojiao1, Caifeng Sun1, Yuli Wei1
1School of Pharmaceutical Sciences, Hebei University, Baoding, China; Key Laboratory of Pharmaceutical Quality Control of Hebei Province, Hebei University, Baoding, China.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|October 31, 2018
Summary
New insulin delivery systems offer improved diabetes management beyond injections. This review explores stimuli-responsive systems, stem cell therapy, and mobile apps for better glucose control and patient compliance.
Area of Science:
- Biomedical Engineering
- Drug Delivery Systems
- Diabetes Therapeutics
Background:
- Insulin is crucial for diabetes management but faces limitations due to its instability and short half-life.
- Current subcutaneous insulin injection methods result in poor glucose control and low patient compliance.
- Novel insulin delivery systems are actively being researched to overcome these challenges.
Purpose of the Study:
- To review various stimuli-responsive insulin delivery systems.
- To describe their response mechanisms and regulation principles.
- To discuss emerging technologies like stem cell transplantation and mobile app-based delivery for diabetes treatment.
Main Methods:
- Literature review of recent advancements in insulin delivery systems.
- Analysis of stimuli-responsive mechanisms (e.g., pH, temperature, glucose).
- Evaluation of stem cell transplantation and mobile application-based delivery technologies.
Main Results:
- Stimuli-responsive systems offer precise insulin release based on physiological cues.
- Stem cell transplantation and mobile apps present innovative approaches for diabetes management.
- Current strategies have distinct advantages and limitations impacting their clinical applicability.
Conclusions:
- Emerging insulin delivery systems show significant promise for improving diabetes care.
- Further research is needed to address challenges and optimize future insulin therapy.
- Integrating advanced technologies can enhance glucose control and patient compliance in diabetes management.
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