Related Experiment Video
Updated: Feb 3, 2026

08:21
Permeabilization of Adhered Cells Using an Inert Gas Jet
Published on: September 4, 2013
10.1K
Ag-Mediated Trifluoromethylthiolation of Inert Csp3-H Bond
Yue Zhao1,2, Jin-Hong Lin2, Xiao-Chun Hang1
1Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM) , Nanjing Tech University (NanjingTech) , 30 South Puzhu Road , Nanjing 211800 , China.
The Journal of Organic Chemistry
|November 1, 2018
Abstract:
Ag-mediated trifluoromethylthiolation of inert Csp3-H bond with CF3SOCl is described. Widely available reagents and operational simplicity make this protocol attractive.
Related Concept Videos
Bond Energies and Bond Lengths
31.5K
Stable molecules exist because covalent bonds hold the atoms together. The strength of a covalent bond is measured by the energy required to break it, that is, the energy necessary to separate the bonded atoms. Separating any pair of bonded atoms requires energy — the stronger a bond, the greater the energy required to break it.
31.5K
Peptide Bonds
83.0K
A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
83.0K
Bonding in Metals
52.4K
Metallic bonds are formed between two metal atoms. A simplified model to describe metallic bonding has been developed by Paul Drüde called the “Electron Sea Model”.
52.4K
Ionic Bonds
130.8K
Overview
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between ions with opposite charges. Ionic compounds are rigid and brittle when solid and may dissociate into their constituent ions in water. Covalent compounds, by contrast, remain intact unless a chemical reaction breaks them.
Opposing Charges Hold Ions Together in Ionic Compounds
Ionic bonds are reversible electrostatic interactions between ions...
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between ions with opposite charges. Ionic compounds are rigid and brittle when solid and may dissociate into their constituent ions in water. Covalent compounds, by contrast, remain intact unless a chemical reaction breaks them.
Opposing Charges Hold Ions Together in Ionic Compounds
Ionic bonds are reversible electrostatic interactions between ions...
130.8K
Valence Bond Theory
50.2K
Overview of Valence Bond Theory
50.2K
Valence Bond Theory
11.3K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
11.3K

