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Percutaneous intervention for symptomatic central vein stenosis in patients with upper limb arteriovenous dialysis
Ashwal Aj1, Abdul Razak Uk1, Padmakumar R1
1Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India, India.
Insights
Endovascular therapy for central venous stenosis in dialysis patients is safe and technically successful. However, multiple interventions are often needed, and long-term patency rates remain suboptimal.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Nephrology
Background:
- Central venous stenosis is a common complication in dialysis patients.
- It significantly impacts the long-term function of arteriovenous access in the upper extremities.
- Symptomatic stenosis can lead to significant ipsilateral limb edema.
Purpose of the Study:
- To evaluate the feasibility and clinical success of endovascular treatment for symptomatic central venous stenosis.
- To assess the outcomes in dialysis patients with upper limb vascular access and limb edema.
Main Methods:
- Retrospective review of hemodialysis patients treated for central venous stenosis between January 2014 and January 2017.
- Analysis of endovascular interventions including percutaneous transluminal angioplasty (PTA) with or without stenting.
- Variable follow-up periods were recorded.
Main Results:
- Ten patients underwent thirteen endovascular interventions with a 100% technical success rate.
- Primary patency rates were 67% at 6 months and 33% at 12 months for PTA with stenting.
- Assisted primary patency was 75% at 6 months, with no immediate complications.
Conclusions:
- Endovascular therapy for central venous stenosis is a safe procedure with a low rate of technical failure.
- The need for multiple interventions is common.
- Long-term patency rates following endovascular treatment are not consistently favorable.
Abstract:
Central venous stenosis is an important hindrance to long-term maintenance of arteriovenous access in the upper extremities in dialysis patients.
Aim:
The present study was done to determine feasibility and clinical success of endovascular approach for the treatment of symptomatic central venous stenosis associated with significant ipsilateral limb edema in dialysis patients with vascular access in the upper limb.
Methods:
A database of hemodialysis patients who underwent endovascular treatment for central venous stenosis from January 2014 to January 2017 at our institute was retrospectively reviewed. Follow-up was variable.
Results:
The study included ten patients (6 men and 4 women) with a mean age of 45.2 years, who underwent thirteen interventions during a period of 3 years. The technical success rate for endovascular treatment was 100%. One patient underwent primary PTA (percutaneous transluminal angioplasty). Seven patients underwent primary PTA and stenting. Three patients underwent secondary PTA. One among these patients underwent secondary PTA twice along with fistuloplasty. One patient underwent secondary PTA with stenting. No immediate complications were encountered during the procedure. Our study shows a primary patency rate of 67% and 33% at 6 months and 12 months for PTA with stenting. Our study also shows secondary or assisted primary patency of 75% at 6 months of follow-up.
Conclusions:
Endovascular therapy (PTA) with or without stenting for central venous stenosis is safe, with low rates of technical failure. Multiple additional interventions are the rule and long-term patency rate is not very good.
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