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Updated: Feb 3, 2026
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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
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Update 2018: 18F-FDG PET/CT and PET/MRI in Head and Neck Cancer
Yasemin Sanli1, Katherine Zukotynski2, Erik Mittra3
1Y.S. is a Visiting Senior Research Fellow, UT Southwestern Medical Center, Dallas, TX.
Clinical Nuclear Medicine
|November 6, 2018
Summary
Recent advances in head and neck cancer treatment include standardized response reporting, F-FDG PET/CT
Area of Science:
- Oncology
- Nuclear Medicine
- Radiation Oncology
Background:
- Head and neck cancers present complex management challenges.
- Accurate assessment of treatment response and novel therapeutic strategies are crucial.
Purpose of the Study:
- To highlight recent significant advancements in head and neck cancer management.
- To underscore progress in diagnostic imaging, treatment response criteria, and therapeutic options.
Main Methods:
- Review of recent multicenter studies and FDA approvals.
- Inclusion of standardized reporting criteria (Hopkins criteria).
- Evaluation of F-FDG PET/CT utility in staging and post-therapy assessment.
Main Results:
- Established negative predictive value of F-FDG PET/CT for N0 neck.
- Demonstrated value of negative post-therapy F-FDG PET/CT for patient management.
- Showcased radiation dose reduction strategies for HPV-related disease.
- FDA approval of nivolumab for recurrent disease.
Conclusions:
- Standardized criteria and advanced imaging like F-FDG PET/CT improve patient management.
- Radiation dose reduction and new immunotherapies offer promising treatment avenues.
- These advances collectively enhance outcomes for head and neck squamous cell carcinoma.
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