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Transplantation of Zebrafish Pediatric Brain Tumors into Immune-competent Hosts for Long-term Study of Tumor Cell Behavior and Drug Response
Published on: May 17, 2017
Self-Reported Executive Dysfunction, Fatigue, and Psychological and Emotional Symptoms in Physically Well-Functioning
Anita Puhr1,2, Ellen Ruud3,4, Vicki Anderson5
1a Department of Psychology , Faculty of Social Sciences, University of Oslo , Oslo , Norway.
Abstract:
Long-term executive function (EF), psychological and emotional difficulties, and fatigue among adult survivors of pediatric brain tumors (PBTs) are sparsely studied. One hundred and fourteen adult PBT survivors, 89 PBT survivor informants, and a healthy control group completed questionnaires assessing these domains. Significant differences between PBT survivors and controls were found on all self-reported measures, most strongly on measures reflecting EF. Patients reported significantly more difficulties with metacognitive aspects of EF compared to behavioral aspects. PBT survivors reported more psychological symptoms and executive dysfunction than their informants. These findings should be taken into consideration in long-term neuropsychological and psychosocial follow-ups.
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